I've made beads on copper wire, then annealed then placed in a muratic acid / hydrogen peroxide mix (50/50). Muratic acid can be found in hardware stores for concrete work or pools and hydrogen peroxide at a beauty store supply shop-- much stronger than what you can buy in the cosmetics section. It took a day or so to eat out the wire-- KJohn's suggestion of making the bead on copper tubing is great, it's what I'll do the next time.
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